Retrospective Analysis of Spray Skin Treats for Severe Burns

Completed

• Conditions: Skin Graft Complications; Morality
• Interventions: Procedure: spray skin; Procedure: Control group

• Registration Number: NCT06170424
• Lead Sponsor: First Affiliated Hospital, Sun Yat-Sen University

Brief Summary

This study investigated the efficacy of novel approach spray skin for extensive severe burns treatment.

Detailed Description

Burns are a global public health problem. This study investigated the efficacy of novel approach spray skin (autologous skin cell suspension combined with split-thickness skin grafting, STSG) for extensive severe burns treatment.

We performed a real-world retrospective analysis of extensive burns patients (\> 50% TBSA) from our hospital last 10 years.

Study Timeline

• Study Start: 2012-01-01
• Primary Completion: 2021-12-31
• Study Completion: 2022-12-31
• Status Verified: 2023-12
• Study First Submitted: 2023-12-03
• Study First Submitted QC: 2023-12-12
• Last Update Submitted: 2023-12-12
• Study First Posted: 2023-12-14
• Last Update Posted: 2023-12-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

• patients with > 50% TBSA

Exclusion Criteria

• died within 1 week after admission
• admitted to hospital more than 1 week after injury

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
experimental gourp	spray skin	The patients who used the autologous skin cell suspension combined with skin grafting.
Control group	Control group	The patients who used split-thickness skin grafting.

Primary Outcome Measures

Name	Time	Method
survival rate	through study completion, an average of 1 year	Patient survival during hospitalization

Secondary Outcome Measures

Name	Time	Method
complication of skin graft	the take rate in the postoperative day 30, 60, 90	the survival of grafting skin
length of hospital	through study completion, usually no more than 6 months	The time during which the patient was hospitalized

Trial Locations

Locations (1)

Department of Burn Surgery, The First Affiliated Hospital of Sun Yat-sen University; 🇨🇳 Guangzhou, Guangdong, China