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Clinical observation on the efficacy of traditional Chinese medicine colonic dialysis in the treatment of chronic kidney disease in stage 3-4

Phase 1
Recruiting
Conditions
chronic kidney disease in stage 3-4
Registration Number
ITMCTR2100004624
Lead Sponsor
onghua Hospital affiliated to Shanghai University of traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1) In accordance with the above western medical diagnostic criteria and TCM syndrome differentiation criteria (spleen and kidney deficiency, turbid toxin internal accumulation syndrome type), and CKD3-4 stage diagnostic criteria (eGFR calculation uses CKD-EPI formula); glomerular filtration rate in patients with glomerular filtration rate of 15: 59 mL/min;
(2) Between 18 and 75 years old, regardless of sex;
(3) Boluntarily participate in the clinical trial and sign the informed consent form.

Exclusion Criteria

(1) Pregnant or lactating women, those who are allergic and intolerant to drugs;
(2) Patients with severe cardio-cerebrovascular disease or liver system disease or tumor, who are in a state of infection, bleeding tendency and mental illness;
(3) Patients who are receiving hormone or immunosuppressive therapy for the primary disease or other diseases or who have received hormone or immunosuppressive therapy within 4 weeks have received renal replacement therapy:
(4) Infection, acidosis, electrolyte disturbance and hypertension were not effectively controlled;
(5) Patients with intestinal diseases. Such as Crohn's disease, irritable bowel syndrome, hemorrhoids, intestinal tumors, hernia, gastrointestinal bleeding, anal fissure and so on.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
eGFR;creatinine;
Secondary Outcome Measures
NameTimeMethod
Cystatin C;BUN;Uric acid;
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