Effect of TaiChi on subthreshold depression in Young Adults

Phase 1

Recruiting

Conditions: Subthreshold Depression

Registration Number: ITMCTR1900002846

Lead Sponsor: Fujian University of Traditional Chinese Medicine, Fuzhou, China

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: Not specified

Inclusion Criteria

1. The Center for Epidemiologic Studies Depression Scale (CES-D) score >=16;
2. According to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-V), the Class A diagnostic criteria for major depressive disorder, met in the last two weeks. More than two and five or fewer participants;
3. Aged 18 to 44 years old, volunteers have a clear sense of consciousness;
4. Has not received any treatment for depression in the past 6 months;
5. In the past six months, he has not engaged in regular exercise (that is, at least 3 times a week, 20 minutes of regular exercise in various forms);
6. No MR examination contraindications;
7. Written informed consent.

Exclusion Criteria

1. According to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-V) criteria, to meet the diagnostic criteria for major depression, bipolar depression, and mental illness;
2. Has a history of major depression in the past 6 months;
3. Recent bereavement;
4. In the use of glucocorticoid drugs,psychotropic drugs or addiction disorders, such as the history of drug abuse and dependence and alcoholism;
5. Suffering from endocrine and metabolic diseases (Cushing's syndrome ,etc.);
6. Have a history of head trauma or a history of serious diseases such as heart, liver and kidney;
7. Pregnant women and lactating women;
8. Other clinical trials who are participating in the evaluation of the results of this study are participating.

Study & Design

Study Type: Interventional study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The 17-item Hamilton Depression Scale (HAMD-17);9-item Patient Health Questionnaire, PHQ-9;

Secondary Outcome Measures

Name	Time	Method
Center of Epidemiological Studies Depression Scale, CES-D;A 7-item Generalized Anxiety Disorder Assessment, GAD-7;Functional magnetic resonance imaging, fMRI;Chinese 14-item perceived stress scale, CPSS;Pittsburgh sleep quality index, PSQI;