We add either Dexamethasone or Ketamine,with Bupivacaine during spinal anaesthesia and we observe the duration of pain free period after surgery with both added drug and will decide which one give more pain free period after surgery.
Not Applicable
- Conditions
- Health Condition 1: S826- Fracture of lateral malleolusHealth Condition 2: S823- Fracture of lower end of tibiaHealth Condition 3: S825- Fracture of medial malleolusHealth Condition 4: S820- Fracture of patellaHealth Condition 5: S824- Fracture of shaft of fibulaHealth Condition 6: S822- Fracture of shaft of tibiaHealth Condition 7: S821- Fracture of upper end of tibiaHealth Condition 8: S829- Unspecified fracture of lower leg
- Registration Number
- CTRI/2022/05/042633
- Lead Sponsor
- Principal investigator Dr Sonik Shah
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Inclusion criteria :
1 Age 18-60 years
2 Lower limb Orthopedic surgery
3 ASA physical status 1 or 2
4 Scheduled for planned Surgery on tibia
5 Patients who could understand and rate their pain on VAS scale (0-10) able to provide written consent
Exclusion Criteria
1 Patientâ??s refusal
2 Emergency surgery
3 Pediatric patient
4 History of Anaphylaxis or Allergy to Local anesthetics
5 History of Bleeding Disorders
6 History of Drug abuse
7 Spine deformity
8 Neurological and cardiac disease
9 Infection at site of Spinal Anesthesia
10 Inability to provide informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patient will be asked for pain and motor recovery every hourly in post operative period in recovery room or in ward, Neurological recovery will also be assessed using Modified Bromage Scale 1 hourly, On patientâ??s request/VAS 4 and Modified Bromage Scale Grade 5, Rescue analgesia of 50 mg Tramadol in 100 ml NS over 20 min to be given.Timepoint: Patient will be asked for pain and motor recovery every hourly in post operative period in recovery room or in ward, Neurological recovery will also be assessed using Modified Bromage Scale 1 hourly, On patientâ??s request/VAS 4 and Modified Bromage Scale Grade 5, Rescue analgesia of 50 mg Tramadol in 100 ml NS over 20 min to be given.
- Secondary Outcome Measures
Name Time Method nausea Vomiting Hypotension SedationTimepoint: One hourly