A study to compare analgesic efficacy of fentanyl versus nalbuphine with ropivacaine in spinal anaesthesia for lower segment caesarean sectio
- Registration Number
- CTRI/2019/06/019827
- Lead Sponsor
- S P medical college and PBM hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
All Patients who will undergo spinal anesthesia for lower segment caesarean section will comprise the study population and will be analyzed prospectively.
1.Patient who is not willing & unable to provide written informed consent to participate in the study.
2.Younger than 18 years & more than 65 years.
3.American Society of Anesthesiologist (ASA) > II class.
4.Patients with history of respiratory disease as those with COPD and other with restrictive or obstructive lung disease.
5.Patients with history of cardiovascular disease, cerebrovascular disease, and severe renal impairment.
6.Allergy or known hypersensitivity to the local anesthetic, or any contraindication to spinal anesthesia.
7.Patients who have coagulation or bleeding abnormalities.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensory and Motor Blockade characteristics and duration <br/ ><br>of postoperative AnalgesiaTimepoint: Sensory and Motor Blockade characteristics: assessed during surgery <br/ ><br>Analgesia effect: assessed during first 24 hours and also assessed need for any rescue analgesics in first 24 hours
- Secondary Outcome Measures
Name Time Method Intraoperative Hemodynamic changes and side effects (e.g. Sedation, Pruritus, <br/ ><br>and Respiratory depression)Timepoint: Hemodynamic changes: assessed Immediately after spinal (T0), 5 min (T5),10 min (T10), 15 min (T15), 20 min (T20), 25 min (T25), 30 min (T30), 45 min (T45) <br/ ><br>Side effects: assessed during first 24 hours