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Multi-component cognitive intervention with physical exercise for older adults with Alzheimer's disease: a 6-month randomized controlled trial

Not Applicable
Conditions
Alzheimer&#39
s disease
Registration Number
JPRN-UMIN000036888
Lead Sponsor
Tohoku University Graduate school, Department of Internal Medicine and Rehabilitation Science
Brief Summary

In all cognitive measures, there were no significant improvements between the two groups after 6 months in the baseline value-adjusted primary analysis. However, the ADAS-cog score was significantly lower between the two groups in secondary analysis adjusted for baseline value, age, sex, and education years. All physical outcomes were significantly higher in the intervention group except for total load compared with baseline measurements.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
33
Inclusion Criteria

Not provided

Exclusion Criteria

1. Not meeting inclusion criteria 2. A serious neurological diagnosis or severe cardiac, pulmonary, and musculoskeletal disorders from physician 3. Regular participation in aerobic exercise or strength training.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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