DRKS00003862
Completed
Not Applicable
Monocentre evaluation of morphological and neurocognitive alterations after whole brain radiotherapy using IMRT technique with hippocampal sparing and boost to the metastases - Hipporad-mono
Klinik für Strahlenheilkunde, Freiburg0 sites3 target enrollmentFebruary 18, 2016
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- C79.3
- Sponsor
- Klinik für Strahlenheilkunde, Freiburg
- Enrollment
- 3
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with 4\-8 brain metastases of solid tumors with indication for WBRT
- •Metastases of 5 \- 35mm width
- •RPA classification I and II
- •Written informed consent
Exclusion Criteria
- •Cerebral lymphoma, metastases from germ cell tumors or SLCL
- •RPA classification III
- •lack of MRI tolerance
- •acute neurologic symptoms demanding immediate therapy
- •accompanying diseases with possible cognitive symptoms or white matter change
- •antiepileptic medication: benzodiazepine, barbiturate, topiramat, hydantoine, valproic acid, carbamazepin
- •demetia, depression, diabetes mellitus
- •hypertensive encephalopathy
- •metastases within the hippocampus or with 10mm range
Outcomes
Primary Outcomes
Not specified
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