DRKS00003862已完成不适用
Monocentre evaluation of morphological and neurocognitive alterations after whole brain radiotherapy using IMRT technique with hippocampal sparing and boost to the metastases - Hipporad-mono
Klinik für Strahlenheilkunde, Freiburg0 个研究点目标入组 3 人开始时间: 2016年2月18日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 3
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Patients with 4-8 brain metastases of solid tumors with indication for WBRT
- •Metastases of 5 - 35mm width
- •RPA classification I and II
- •Written informed consent
排除标准
- •Cerebral lymphoma, metastases from germ cell tumors or SLCL
- •RPA classification III
- •lack of MRI tolerance
- •acute neurologic symptoms demanding immediate therapy
- •accompanying diseases with possible cognitive symptoms or white matter change
- •antiepileptic medication: benzodiazepine, barbiturate, topiramat, hydantoine, valproic acid, carbamazepin
- •demetia, depression, diabetes mellitus
- •hypertensive encephalopathy
- •metastases within the hippocampus or with 10mm range
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