Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): 10 Year Onsite Follow-up
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 225
- 主要终点
- Pain subscale of the Knee Injury and Osteoarthritis Score (KOOS).
研究概览
简要总结
In this study the investigators will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction surgery, aspects of the original injury and repair, and patient characteristics are risk factors for osteoarthritis after ACL reconstruction surgery.
详细描述
The purpose of this study is to identify risk factors for signs and symptoms of osteoarthritis two and ten year post ACL reconstruction from information available at the time of surgery. Hypothesis: Smoking status, older age, higher BMI, increased severity of cartilage injuries, increased meniscal resection, revision surgery, and incidence of additional arthroscopic procedures will result in more symptoms and signs of osteoarthritis at 10-year follow-up.
Primary outcome measures will be the joint space width measured on weight-bearing radiographs, as well as the pain subscale of the Knee Injury and Osteoarthritis Score (KOOS).
Secondary outcome measures will include the knee related quality of life subscale of the Knee Injury and Osteoarthritis Score (KOOS).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Had primary unilateral ACL reconstruction performed by Dr. Kurt Spindler (Vanderbilt University), Dr. Christopher Kaeding (The Ohio State University), Dr. Rick Parker (Cleveland Clinic), Dr. Jack Andrish (Cleveland Clinic), Dr. Rick Wright (Washington University, St. Louis), or Dr. Matthew Matava (Washington University, St. Louis).
- •Participated in the 2 yr onsite visit
排除标准
- •Unable to be consented
- •Unable to participate for health reasons
- •History of intra-articular knee infection
- •History of total knee arthroplasty on either knee
结局指标
主要结局
Pain subscale of the Knee Injury and Osteoarthritis Score (KOOS).
时间窗: 10 years after ACL reconstruction surgery
Joint space width measured on weight-bearing radiographs
时间窗: 10 years after ACL reconstruction surgery
次要结局
- Knee related quality of life subscale of the Knee Injury and Osteoarthritis Score (KOOS)(10 years after ACL reconstruction surgery)
研究者
Kurt P. Spindler
Adjoint Professor
Vanderbilt University Medical Center