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临床试验/NCT02717559
NCT02717559
已完成
不适用

Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): 10 Year Onsite Follow-up

Vanderbilt University Medical Center0 个研究点目标入组 225 人2016年3月1日

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Osteoarthritis
发起方
Vanderbilt University Medical Center
入组人数
225
主要终点
Pain subscale of the Knee Injury and Osteoarthritis Score (KOOS).
状态
已完成
最后更新
3个月前

概览

简要总结

In this study the investigators will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction surgery, aspects of the original injury and repair, and patient characteristics are risk factors for osteoarthritis after ACL reconstruction surgery.

详细描述

The purpose of this study is to identify risk factors for signs and symptoms of osteoarthritis two and ten year post ACL reconstruction from information available at the time of surgery. Hypothesis: Smoking status, older age, higher BMI, increased severity of cartilage injuries, increased meniscal resection, revision surgery, and incidence of additional arthroscopic procedures will result in more symptoms and signs of osteoarthritis at 10-year follow-up. Primary outcome measures will be the joint space width measured on weight-bearing radiographs, as well as the pain subscale of the Knee Injury and Osteoarthritis Score (KOOS). Secondary outcome measures will include the knee related quality of life subscale of the Knee Injury and Osteoarthritis Score (KOOS).

注册库
clinicaltrials.gov
开始日期
2016年3月1日
结束日期
2025年12月1日
最后更新
3个月前
研究类型
Observational
性别
All

研究者

责任方
Principal Investigator
主要研究者

Kurt P. Spindler

Adjoint Professor

Vanderbilt University Medical Center

入排标准

入选标准

  • Had primary unilateral ACL reconstruction performed by Dr. Kurt Spindler (Vanderbilt University), Dr. Christopher Kaeding (The Ohio State University), Dr. Rick Parker (Cleveland Clinic), Dr. Jack Andrish (Cleveland Clinic), Dr. Rick Wright (Washington University, St. Louis), or Dr. Matthew Matava (Washington University, St. Louis).
  • Participated in the 2 yr onsite visit

排除标准

  • Unable to be consented
  • Unable to participate for health reasons
  • History of intra-articular knee infection
  • History of total knee arthroplasty on either knee

结局指标

主要结局

Pain subscale of the Knee Injury and Osteoarthritis Score (KOOS).

时间窗: 10 years after ACL reconstruction surgery

Joint space width measured on weight-bearing radiographs

时间窗: 10 years after ACL reconstruction surgery

次要结局

  • Knee related quality of life subscale of the Knee Injury and Osteoarthritis Score (KOOS)(10 years after ACL reconstruction surgery)

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