Hypothyroidism and its management with Ayurveda

Phase 1/2

Recruiting

• Conditions: HYPOTHYROIDISM

• Registration Number: CTRI/2013/08/003917
• Lead Sponsor: Institute for Post GraduateTeaching and Reseach in Ayurveda Gujarat Ayurveda University Jamnagar

Brief Summary

The present study is designed with the aims to study to evaluate the efficacy of Vamana karma in the management of Hypothyroidism, to study to evaluate the efficacy of Virechana karma in the management of Hypothyroidism after this as shamana drug PUNARANAVA AMRUTA GUGGULU in both groups and group C is controle with tablet Levothyroxine sodium



**IN GROUP A VAMANA KARMA**



Deepan pachana                           Trikatu churna            2g TDS with luke warm water         3-7days



Snehpan                                         Go ghrita                     as per Koshtha                                  3-7days

Abhyanga and Swedana             Bala oil                         2 times a day                                     1day



vamana yoga(1day)                      Madanphalapippali   6-10g



Vacha  churna             2-5g

Saidhava                      5-10g

Honey                           50ml



Yastimadhu phant     2-3 Liter



samsarjana karma                               Diet (as per shuddhi) 3-7days



**IN GROUP B VIRECHANA KARMA**



Deepan pachana(as



Snehpana(as above)



Abhyanga Swedana               Bala oil                                      3days



Virechana yoga(1 day)                        Trikatu churna         2g



Triphala churna      5g



Danti churna           10g



Trivritta churna        10g



Chitraka churna      1g



Snuhikshira             10ml



Gudodaka                40-80ml



Samsarjana karma (as per shuddhi)                                                                                            3-7 days



**Internal Shamana yoga    :Punaranava amruta guggulu**              1g tds(2 tablets each 500mg)     ANUPAN:Luke warm water          45 days



**GROUP C :** Standered controle        Tab Levothyroxine sodium   dose :as per  physician prescribe    45 days



**CRITERIYA FOR ASSESSMENT:**

**The efficacy of treatment will be assessed on the basis of relief in signs and symptoms**

**On the basis of changes in the laboratory investigation**

**Status of Dosha,Dushya and Agni will be assessed before after treatment**

**FOLLOW UP:**

**Follow up will be done for four weeks after the complition of****treatment to see the long standing effect of the treatment.**

**Patients will be redirected to regular OPD treatment after the stipulated time of research work.**

Detailed Description

Not available

Study Timeline

• Study Start: 2013-05-02
• Last Update Posted: 2013-08-23

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

Patients with clinical features of Hypothyroidism namely increase level of serum TSH decrease level of serum T3 serum T4 irregular menstruation weakness fatigue weight gain hair fall constipation puffiness of face bilateral peripheral edema dry and coarse skin palpitation cold intolerance lethargy.

Exclusion Criteria

Patients with Ischemic heart diseases Uncontrolled hypertension Myocardial infarction Cardiovascular event Cardiac arrhythmia Pregnancy Active malignant disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The efficacy of treatment will be assessed on the basis of relief in signs and symptoms Evaluation of BIOCHEMICAL parameters such as serum TSH serum T3 and T4 in all groups with Hematological Urine routine and microscopic examination before and after treatment	60 Days in two interventional group A B and 45 Days in Controle group

Secondary Outcome Measures

Name	Time	Method
Exacerbation in signs and symptoms	4 Weeks

Trial Locations

Locations (1)

Institute for Post Graduate Teaching and Research in Ayurveda; 🇮🇳 Jamnagar, GUJARAT, India

Institute for Post Graduate Teaching and Research in Ayurveda

🇮🇳Jamnagar, GUJARAT, India

Dr pratiksha pateriya

Principal investigator

9601916926

drpratikshaayu@gmail.com