跳至主要内容
临床试验/NCT02990273
NCT02990273终止不适用

The Utility of Thromboelastography in Cirrhotic Patients Undergoing Endoscopic Procedures

Johns Hopkins University0 个研究点目标入组 1 人开始时间: 2017年1月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
入组人数
1
主要终点
Units of fresh frozen plasma (FFP) and platelet transfused

研究概览

简要总结

Cirrhosis results in decreased synthesis of both procoagulants and anticoagulants resulting in "rebalanced homeostasis". However, conventional blood tests (platelets/ INR levels) that are performed prior to invasive procedures do not accurately reflect the coagulation changes that occur in cirrhotics, resulting in unnecessary transfusion of blood products. Thromboelastography (TEG) is a global hemostasis assessment tool that is being used in surgery (including liver transplant) to help guide blood product transfusion in the operating room. The investigators would like to compare the use of TEG vs. INR/platelets to help guide blood product transfusion in cirrhotic patients undergoing inpatient endoscopy. The investigators will evaluate to see if there is a decrease in prophylactic blood transfusions prior to endoscopy when using TEG.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All 18 yo + cirrhotic patients who are being scheduled for inpatient endoscopy

排除标准

  • Patients on blood thinners (prophylactic anticoagulation is permissible)
  • Hemodynamically unstable patients requiring pressors (ie ICU level patients)
  • Pregnant or lactating individuals
  • Inability to provide consent for any reason

结局指标

主要结局

Units of fresh frozen plasma (FFP) and platelet transfused

时间窗: 2 week

Will compare how much FFP and platelet transfusion patients receiving between 2 groups.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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