The Utility of Thromboelastography in Cirrhotic Patients Undergoing Endoscopic Procedures
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 1
- 主要终点
- Units of fresh frozen plasma (FFP) and platelet transfused
研究概览
简要总结
Cirrhosis results in decreased synthesis of both procoagulants and anticoagulants resulting in "rebalanced homeostasis". However, conventional blood tests (platelets/ INR levels) that are performed prior to invasive procedures do not accurately reflect the coagulation changes that occur in cirrhotics, resulting in unnecessary transfusion of blood products. Thromboelastography (TEG) is a global hemostasis assessment tool that is being used in surgery (including liver transplant) to help guide blood product transfusion in the operating room. The investigators would like to compare the use of TEG vs. INR/platelets to help guide blood product transfusion in cirrhotic patients undergoing inpatient endoscopy. The investigators will evaluate to see if there is a decrease in prophylactic blood transfusions prior to endoscopy when using TEG.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All 18 yo + cirrhotic patients who are being scheduled for inpatient endoscopy
排除标准
- •Patients on blood thinners (prophylactic anticoagulation is permissible)
- •Hemodynamically unstable patients requiring pressors (ie ICU level patients)
- •Pregnant or lactating individuals
- •Inability to provide consent for any reason
结局指标
主要结局
Units of fresh frozen plasma (FFP) and platelet transfused
时间窗: 2 week
Will compare how much FFP and platelet transfusion patients receiving between 2 groups.
次要结局
未报告次要终点
