Phase II randomized clinical trial to investigate efficacy of zoledronic acid for the patients with metastatic or advanced breast cancer
Phase 2
- Conditions
- Metastatic breast cancer
- Registration Number
- JPRN-UMIN000027382
- Lead Sponsor
- Kyushu Breast Cancer Study Group (KBC-SG)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
Not provided
Exclusion Criteria
1) There is any infection or complication of teeth 2) History of allergy by zoledronic acud 3) Patients with osteoporosis who needs therapy by bisphosphonates
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Progression free survival, PFS
- Secondary Outcome Measures
Name Time Method Response rate, RR clinical benefit rate (after 24 weeks) Skeletal related events, SRE Time to bone metastasis