Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo

Not Applicable

Recruiting

• Conditions: Vitiligo

• Registration Number: NCT06410898
• Lead Sponsor: Sohag University

Brief Summary

The present study will aim to evaluate:

1. The presence of Hypoxia Inducible Factor in vitiligo patient

2. Defect of Autophagy Related Genes in vitiligo patient

3. The cross relation between Autophagy Related Genes and Hypoxia Inducible Factor in the pathogenesis of vitiligo among Egyptian patients in Sohag Governorate

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-25
• Status Verified: 2024-05
• Study First Submitted: 2024-05-02
• Study First Submitted QC: 2024-05-07
• Last Update Submitted: 2024-05-07
• Study First Posted: 2024-05-13
• Last Update Posted: 2024-05-13
• Primary Completion: 2024-07-25
• Study Completion: 2024-07-25

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Adult >18 years
• With non segmental vitiligo
• A group of participants will be included as a control group

Exclusion Criteria

• Pregnancy
• Patient with chronic inflammatory skin disorders
• patient on anti-oxidant or anti-inflammatory drugs
• patient on topical or systemic treatment for vitiligo in last 4 weeks
• patients with other autoimmune diseases
• patients with diabetes mellitus

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Assessment of Autophagy Related genes in Vitiligo patients	2 months	Assess Autophagy Related genes levels in skin biopsy of vitiligo patient
Assessment of Hypoxia Inducible Factor in Vitiligo patients	2 months	Assess level of Hypoxia Inducible factor in skin biopsy of vitiligo patient

Trial Locations

Locations (1)

Sohag University hospitals; 🇪🇬 Sohag, Egypt