Short-term efficacy of K-CAB 50 mg (tegoprazan) compared with Nexium 20 mg (esomeprazole magnesium) in patients with non-erosive reflux disease with nocturnal heartburn symptom

Inje University Haeundae Paik Hospital0 个研究点目标入组 160 人开始时间: 待定最近更新: 2020年3月23日

适应症

试验速览

暂无简介。

•1) Only adult men and women over 19 years old
•2) Those who have complained of heartburn at least 6 months prior to Visit 1
•3) No mucosal break was observed according to LA classification in the upper gastrointestinal endoscopy performed by the institution within 28 days before the start of investigational drug administration.
•4) Those who have a GERD-Q questionnaire score of 8 or higher in the screening test
•5) Those who complain of nighttime heartburn more than 3 times a week

•1) Those who cannot receive an upper gastrointestinal endoscopy
•2) Upper gastrointestinal endoscopy shows esophageal stricture, gastrointestinal varices, Barrett's esophagus, active peptic ucler, GI bleeding, or eosinophilic esophagitis
•3) Those who received surgery on esophagus, stomach or duodenum
•4) Those who have hypersensitivity reactions to medicines for clinical trials
•5) Pregnant women, lactating women

发起方

Inje University Haeundae Paik Hospital