RECOVERY OF MICROVASCULAR MYOCARDIAL RESISTANCE AFTER ST ELEVATION MYOCARDIAL INFARCTION AND ITS RELATION TO OUTCOME - microvascular resistance STEMI study

Catharina-ziekenhuis0 个研究点目标入组 50 人开始时间: 待定最近更新: 2024年4月15日

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•* Patients with STEMI * 12 hours and with ST deviation * 5 mm. Who have one or more other lesions mandating FFR or PCI in de following days after PCI of the culprit artery;INCLUSION CRITERIA
•* Age between 18 and 75 years
•* Presentation within 12 hours after the onset of complaints
•* Acute ST-elevation myocardial infarction with a total ST segment deviation *5 mm
•* Able to give and understand informed consent
•* Culprit lesion in a proximal or mid-segment of one of the major coronary arteries (diameter *2,5 mm), which is stented successfully
•* Stable condition after stenting
•* One or more additional lesions in one or more different coronary arteries, mandating FFR measurement +/- PPCI during the subacute phase

•* Age less than 18 years or more than 75 years
•* Cardiogenic shock or pre-shock
•* Patients with previous myocardial infarction in the culprit artery or with previous bypass surgery
•* Very tortuous or calcified coronary arteries
•* Long or complex PCI
•* Severe concomitant disease or conditions with a life expectancy of less than 1 year
•* Inability to understand and give informed consent
•* Known myocardial diseases such as moderate or severe left ventricular hypertrophy or cardiomyopathy
•* Pregnancy
•* Severe conduction disturbances necessitating implantation of a temporary pacemaker
•* Contraindications for MRI (claustrophobia, ferromagnetic metal fragments in the body)

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