跳至主要内容
临床试验/NCT06372951
NCT06372951尚未招募不适用

Role of Lung Ultrasound in Assessment of Neonatal Respiratory Distress

Assiut University0 个研究点目标入组 132 人开始时间: 2024年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
132
主要终点
Identifying causes of neonatal respiratory distress

研究概览

简要总结

Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .

详细描述

  • Lung disease is the most common cause of neonatal respiratory distress.

  • It can result in respiratory failure and death in severe cases.

  • The mortality rate is approximately 11%:32%.

  • Identification of the etiology of lung disease is important for neonatologists.

  • Traditionally, chest X-ray has been considered as the most valuable imaging modality for the diagnosis of lung diseases, but it unavoidably causes radiation damage to the patient.

  • Neonates are susceptible to radiation because they have rapidly dividing cells that cannot repair mutated DNA.

  • The risk of cancer induction in infants receiving a single small dose of radiation is 2-3 times higher than the average population and 6-9 times higher than the risk from an exposure of a 60-year-old patient.

  • New imaging modalities have been introduced in clinical practice in recent years such as lung ultrasound.

  • One of the most common causes of neonatal respiratory distress that can be diagnosed by ultrasound is :Respiratory Distress Syndrome:

  • Respiratory distress syndrome.. is a major cause of neonatal mortality.

  • It mainly occur in preterm infants due to structural and functional lung immaturity.

  • Pulmonary surfactant insufficiency is an important pathogenesis in respiratory distress syndrome.

  • The ultrasonic features of respiratory distress syndrome are: Compact B-Lines, white lung appearance, abnormality in pleural line (thick and irregular),lung consolidation.

  • Lung ultrasound has the advantages of :

  • Non-ionizing.

  • Easy to operate.

  • Low coast.

  • Portable for bedside use.

  • The imaging is performed in real-time.

  • Thus making it as a potential tool to be used in neonatal intensive care units.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
1 Day 至 28 Days(Child)
性别
All
接受健康志愿者

入选标准

  • Neonates in neonatal intensive care units

排除标准

  • Patients with poor-quality of lung ultrasound image.
  • Subcutaneous emphysema.

结局指标

主要结局

Identifying causes of neonatal respiratory distress

时间窗: Baseline

- To evaluate lung ultrasound accuracy and reliability in diagnosing pulmonary disease in neonates in comparison to x rays

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Esraa Talat Fawzy

: Assistant Lecturer

Assiut University

相似试验

Lung Ultrasound in Neonatal Intensive Care Units | 临床试验