Role of Lung Ultrasound in Assessment of Neonatal Respiratory Distress
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 132
- 主要终点
- Identifying causes of neonatal respiratory distress
研究概览
简要总结
Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .
详细描述
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Lung disease is the most common cause of neonatal respiratory distress.
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It can result in respiratory failure and death in severe cases.
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The mortality rate is approximately 11%:32%.
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Identification of the etiology of lung disease is important for neonatologists.
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Traditionally, chest X-ray has been considered as the most valuable imaging modality for the diagnosis of lung diseases, but it unavoidably causes radiation damage to the patient.
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Neonates are susceptible to radiation because they have rapidly dividing cells that cannot repair mutated DNA.
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The risk of cancer induction in infants receiving a single small dose of radiation is 2-3 times higher than the average population and 6-9 times higher than the risk from an exposure of a 60-year-old patient.
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New imaging modalities have been introduced in clinical practice in recent years such as lung ultrasound.
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One of the most common causes of neonatal respiratory distress that can be diagnosed by ultrasound is :Respiratory Distress Syndrome:
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Respiratory distress syndrome.. is a major cause of neonatal mortality.
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It mainly occur in preterm infants due to structural and functional lung immaturity.
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Pulmonary surfactant insufficiency is an important pathogenesis in respiratory distress syndrome.
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The ultrasonic features of respiratory distress syndrome are: Compact B-Lines, white lung appearance, abnormality in pleural line (thick and irregular),lung consolidation.
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Lung ultrasound has the advantages of :
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Non-ionizing.
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Easy to operate.
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Low coast.
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Portable for bedside use.
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The imaging is performed in real-time.
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Thus making it as a potential tool to be used in neonatal intensive care units.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 1 Day 至 28 Days(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Neonates in neonatal intensive care units
排除标准
- •Patients with poor-quality of lung ultrasound image.
- •Subcutaneous emphysema.
结局指标
主要结局
Identifying causes of neonatal respiratory distress
时间窗: Baseline
- To evaluate lung ultrasound accuracy and reliability in diagnosing pulmonary disease in neonates in comparison to x rays
次要结局
未报告次要终点
研究者
Esraa Talat Fawzy
: Assistant Lecturer
Assiut University
