Skip to main content
Clinical Trials/NCT06372951
NCT06372951
Not yet recruiting
Not Applicable

Role of Lung Ultrasound in Assessment of Neonatal Respiratory Distress

Assiut University0 sites132 target enrollmentMay 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Neonatal Respiratory Distress
Sponsor
Assiut University
Enrollment
132
Primary Endpoint
Identifying causes of neonatal respiratory distress
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .

Detailed Description

* Lung disease is the most common cause of neonatal respiratory distress. * It can result in respiratory failure and death in severe cases. * The mortality rate is approximately 11%:32%. * Identification of the etiology of lung disease is important for neonatologists. * Traditionally, chest X-ray has been considered as the most valuable imaging modality for the diagnosis of lung diseases, but it unavoidably causes radiation damage to the patient. * Neonates are susceptible to radiation because they have rapidly dividing cells that cannot repair mutated DNA. * The risk of cancer induction in infants receiving a single small dose of radiation is 2-3 times higher than the average population and 6-9 times higher than the risk from an exposure of a 60-year-old patient. * New imaging modalities have been introduced in clinical practice in recent years such as lung ultrasound. * One of the most common causes of neonatal respiratory distress that can be diagnosed by ultrasound is :Respiratory Distress Syndrome: * Respiratory distress syndrome.. is a major cause of neonatal mortality. * It mainly occur in preterm infants due to structural and functional lung immaturity. * Pulmonary surfactant insufficiency is an important pathogenesis in respiratory distress syndrome. * The ultrasonic features of respiratory distress syndrome are: Compact B-Lines, white lung appearance, abnormality in pleural line (thick and irregular),lung consolidation. * Lung ultrasound has the advantages of : * Non-ionizing. * Easy to operate. * Low coast. * Portable for bedside use. * The imaging is performed in real-time. * Thus making it as a potential tool to be used in neonatal intensive care units.

Registry
clinicaltrials.gov
Start Date
May 1, 2024
End Date
March 2026
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Esraa Talat Fawzy

: Assistant Lecturer

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Neonates in neonatal intensive care units

Exclusion Criteria

  • Patients with poor-quality of lung ultrasound image.
  • Subcutaneous emphysema.

Outcomes

Primary Outcomes

Identifying causes of neonatal respiratory distress

Time Frame: Baseline

- To evaluate lung ultrasound accuracy and reliability in diagnosing pulmonary disease in neonates in comparison to x rays

Similar Trials