Lung Ultrasound in Neonatal Intensive Care Units
- Conditions
- Neonatal Respiratory Distress
- Registration Number
- NCT06372951
- Lead Sponsor
- Assiut University
- Brief Summary
Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .
- Detailed Description
* Lung disease is the most common cause of neonatal respiratory distress.
* It can result in respiratory failure and death in severe cases.
* The mortality rate is approximately 11%:32%.
* Identification of the etiology of lung disease is important for neonatologists.
* Traditionally, chest X-ray has been considered as the most valuable imaging modality for the diagnosis of lung diseases, but it unavoidably causes radiation damage to the patient.
* Neonates are susceptible to radiation because they have rapidly dividing cells that cannot repair mutated DNA.
* The risk of cancer induction in infants receiving a single small dose of radiation is 2-3 times higher than the average population and 6-9 times higher than the risk from an exposure of a 60-year-old patient.
* New imaging modalities have been introduced in clinical practice in recent years such as lung ultrasound.
* One of the most common causes of neonatal respiratory distress that can be diagnosed by ultrasound is :Respiratory Distress Syndrome:
* Respiratory distress syndrome.. is a major cause of neonatal mortality.
* It mainly occur in preterm infants due to structural and functional lung immaturity.
* Pulmonary surfactant insufficiency is an important pathogenesis in respiratory distress syndrome.
* The ultrasonic features of respiratory distress syndrome are: Compact B-Lines, white lung appearance, abnormality in pleural line (thick and irregular),lung consolidation.
* Lung ultrasound has the advantages of :
* Non-ionizing.
* Easy to operate.
* Low coast.
* Portable for bedside use.
* The imaging is performed in real-time.
* Thus making it as a potential tool to be used in neonatal intensive care units.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 132
- Neonates in neonatal intensive care units
- Patients with poor-quality of lung ultrasound image.
- Subcutaneous emphysema.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identifying causes of neonatal respiratory distress Baseline - To evaluate lung ultrasound accuracy and reliability in diagnosing pulmonary disease in neonates in comparison to x rays
- Secondary Outcome Measures
Name Time Method