Termination of Early Pregnancy in Scarred Uterus With Lletrozole and Misoprostol Compared to Misoprostol Alone

• Conditions: Termination of Early Pregnancy in Scarred Uterus
• Interventions: Drug: Letrozole 2.5mg

• Registration Number: NCT05067309
• Lead Sponsor: Ahmed Elsayed Aref

Brief Summary

Termination of early pregnancy in scarred uterus with letrozole and misoprostol compared to Misoprostol alone

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-09
• Study First Submitted: 2021-09-23
• Study First Submitted QC: 2021-09-23
• Last Update Submitted: 2021-09-23
• Study Start: 2021-10-01
• Study First Posted: 2021-10-05
• Last Update Posted: 2021-10-05
• Primary Completion: 2022-04-01
• Study Completion: 2022-08-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 1

Inclusion Criteria

• Minimum age of 18 years for mother.

  • Non-viable fetus (missed abortion or blighted ovum) in the 1st trimester of pregnancy evidenced by criteria for diagnosis by TVS .
  • Previous C.S or Myomectomy (1 or more )
  • lack of any maternal diseases such as: heart disease, asthma, history of thromboembolism, cancer, renal failure, and liver diseases.

Exclusion Criteria

• * Medical problem in patient

  • Emergency conditions which need intervention .
  • History of allergy to misoprostol or letrozole drugs.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Missed abortion received letrozole then misoprostol	Letrozole 2.5mg	-

Primary Outcome Measures

Name	Time	Method
Complete abortion of early pregnancy with letrozole then misoprostol	6 months	Letrozole increase cervical ripening

Trial Locations

Locations (1)

Ahmed Elsayed Aref; 🇪🇬 Sohag, Egypt