An Open-Label, Single Dose Study to Investigate Striatal Dopamine D2 Receptor Binding of JNJ-37822681 Using [11C]Raclopride Positron Emission Tomography in Healthy Male Subjects
- Conditions
- schizophrenia10039628
- Registration Number
- NL-OMON30989
- Lead Sponsor
- Johnson & Johnson Pharmaceutical
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 8
Inclusion Criteria
healthy male subjects between 18 - 55 years of age
BMI between 18 and 30 kg/m²
Exclusion Criteria
History of, or currently active, significant illness or medical disorder
Yearly cumulative dose due to exposure to radiation above 10 mSv
Any significant MR abnormalities as determined by a neuroradiologist
Metal implants
Claustrophobia
History of epilepsy or fits or unexplained black-outs
Significant history of or current psychiatric or neurological disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method