Study on the clinical efficacy and mechanism of constant gliflozin tablets in the treatment of microalbuminuria in type 2 diabetic nephropathy
- Conditions
- Type 2 diabetic nephropathy
- Registration Number
- ChiCTR2400088947
- Lead Sponsor
- The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) Patients who meet the diagnostic criteria for microalbuminuria phase of type 2 diabetic nephropathy; <br>(2) Aged 18 to 70 years old (including 18 and 70), gender is not limited; <br>(3)7.0% <= HbA1c <= 11%; <br>(4) The subject was informed and voluntarily signed the informed consent form.
(1) Patients with type 1 diabetes mellitus, gestational diabetes mellitus and other special types of diabetes mellitus; <br>(2) Kidney damage caused by non-diabetic nephropathy; <br>(3) Blood pressure >=160 / 100mmHg; <br>(4) Patients with acute complications of diabetes mellitus; <br>(5) Severe cardiac and cerebrovascular diseases and serious primary diseases, such as liver, kidney and hematopoietic system; (6) People with known allergies and allergic constitution to the study drug; <br>(7) Pregnant and lactating women and women with recent family planning; <br>(8) Long-term alcoholism, drug dependence, and patients with mental illness; <br>(9) Those who have participated in or are participating in other drug clinical trials within one month before the screening period of the study; <br>(10) The glomerular filtration rate is <45 ml min^(-1)*(1.73 m²)^(-1); <br>(11) The investigator is not inappropriate to attend the clinical investigator.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Urinary albumin / creatinine;
- Secondary Outcome Measures
Name Time Method fasting blood-glucose;glycosylated hemoglobin ;Blood glucose was obtained 2h after meal;G. F. R. ;