Cisatracurium generic vs original brand-name

Not Applicable

Completed

• Conditions: Patients admitted to ICU, under optimized sedation and ventilation, for hypoxemic acute respiratory failure with a PaO2/FIO2 < 200 and requiring paralysis to improve gas exanges and offset patient-ventilator asynchronies.; Respiratory; Hypoxemic acute respiratory failure

• Registration Number: ISRCTN89942618
• Lead Sponsor: Farhat Hached University Hospital

Brief Summary

2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33738034/ (added 21/11/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-03-31
• Study Start: 2017-10-30
• Last Update Posted: 4 December 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

1. Patients admitted to the ICU with severe acute respiratory failure with severe hypoxemia (ratio of arterial oxygen partial pressure to fractional inspired oxygen (PaO2/FiO2) < 200),
2. Put under invasive mechanical ventilation with important patient-ventilator asynchrony and requiring paralysis despite deep analgo-sedation as assessed by RSS
3. Aged 18 and older

Exclusion Criteria

1. Patients with history of allergy to cisatracurium
2. Malignant hyperthermia
3. Pregnancy
4. Neuromuscular disorders

Study & Design

• Study Type: Interventional
• Study Design: Not specified