Effect of Folic Acid Supplementation among Diabetic Polyneuropathy Patients
Early Phase 1
- Conditions
- Diabetic Polyneuropathy.Type 2 diabetes mellitus with diabetic polyneuropathyE11.42
- Registration Number
- IRCT20121216011763N22
- Lead Sponsor
- Vice chancellor for research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
>20 Years Old Diabetic Neuropathy Approved by the Neurologist Desire to Consume Folic Acid during 8 Weeks
Exclusion Criteria
Non-Diabetic Neuropathic Patients Pregnant Women Alcohol Users Smoking Multivitamin-minerals Containing Folic Acid, B12 and B6 Consumers during Study Drugs Consumers that may Interfere with the Absorption Folic Acid such as methotrexate, bacterium, antiepileptic and sulfa antibiotics
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method erve Conduction Velocity. Timepoint: week 0 and week 8. Method of measurement: EMG-NCV.;Serum folic acid. Timepoint: week 0 and week 8. Method of measurement: Laboratory analysis (blood test).;Serum vitamin B12. Timepoint: week 0 and week 8. Method of measurement: Laboratory analysis (blood test).;Serum homocystein. Timepoint: week 0 and week 8. Method of measurement: Laboratory analysis (blood test).
- Secondary Outcome Measures
Name Time Method CRP. Timepoint: Week 0 and week 8. Method of measurement: Laboratory analysis (blood test).;HbA1C. Timepoint: Week 0 and week 8. Method of measurement: Laboratory analysis (blood test).