Transfer and Ultrafiltration In Peritoneal Dialysis

Not Applicable

Terminated

• Conditions: End-stage Renal Disease

• Registration Number: NCT02474719
• Lead Sponsor: Centre Hospitalier Universitaire de Besancon

Brief Summary

The aim of this study is to demonstrate the efficiency of an adapted and "alternate" peritoneal dialysis scheme in terms of sodium extraction and purification compared to an adapted conventional peritoneal dialysis scheme.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2015-06-03
• Study First Submitted QC: 2015-06-15
• Study First Posted: 2015-06-18
• Status Verified: 2017-02
• Primary Completion: 2018-07-18
• Study Completion: 2018-07-18
• Last Update Submitted: 2019-08-05
• Last Update Posted: 2019-08-07

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• Patients hospitalized in the Nephrology department of the Besançon University Hospital
• Patients treated by continuous ambulatory peritoneal dialysis or ambulatory peritoneal dialysis for at least 6 months
• Absence of hospitalization caused by an infection in the month prior to inclusion
• Patients with a ratio (D / P) of the concentration of creatinine in the blood and dialysate between 0.5 and 0.8 on a checkup of less than 1 year.
• No contraindication to the use of hypertonic bag
• Signature of informed consent for participation indicating that the subject has understood the purpose and procedures required by the study and agrees to participate in the study and comply with the requirements and limitations inherent in this study
• Affiliation to a French social security system or beneficiary

Exclusion Criteria

• Legal incapacity or limited legal capacity
• Patients unlikely to cooperate in the study and/or low cooperation anticipated by the investigator
• Patients without health insurance
• Pregnant women
• Patient being in the exclusion period from another study or planned by the "national register of volunteers"
• Hospitalization caused by an infection in the month prior to inclusion
• Patients with a peritoneal dialysis catheter dysfunction

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Intra-dialytic concentrations of different electrolytes (sodium, phosphorus, urea, creatinine, glucose and proteins)	In a maximum of 72 hours after collection

Trial Locations

Locations (1)

Besançon University Hospital, Nephrology Department; 🇫🇷 Besançon, Franche-Comté, France