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Antihypertensive Efficacy and Safety of Approved Drugs in Japanese Patients With Essential Hypertension (Banyu Study)(0954A-302)

Phase 3
Completed
Conditions
Hypertension
Registration Number
NCT00092209
Lead Sponsor
Organon and Co
Brief Summary

The purpose of this study is to evaluate antihypertensive (lowering blood pressure) effectiveness of three combinations of approved study drugs compared to both study drugs being given alone.

Detailed Description

The duration of treatment is 3.5 months.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
840
Inclusion Criteria
  • Japanese ancestry
  • Stable high blood pressure defined by the study criteria
Exclusion Criteria
  • Pregnant or nursing
  • Significant concurrent kidney, liver, blood, or other disease
  • Recent heart attack or heart surgery
  • History of stroke, severe hypertension (high blood pressure), significant heart failure or cardiac arrhythmias
  • Significant lab abnormalities
  • Uncontrolled blood sugar
  • History of certain drug allergies

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Mean trough SiDBP after 8 weeks of treatment
Secondary Outcome Measures
NameTimeMethod
Safety
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