NCT00092209已完成3 期
A Randomized, Placebo-Controlled, Double-Blind, Parallel Study of the Anti-Hypertensive Efficacy and Safety of Losartan Monotherapy as Compared to HCTZ Monotherapy and to the Combination of Losartan and HCTZ in Japanese Patients With Essential Hypertension
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 840
- 主要终点
- Mean trough SiDBP after 8 weeks of treatment
研究概览
简要总结
The purpose of this study is to evaluate antihypertensive (lowering blood pressure) effectiveness of three combinations of approved study drugs compared to both study drugs being given alone.
详细描述
The duration of treatment is 3.5 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 25 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Japanese ancestry
- •Stable high blood pressure defined by the study criteria
排除标准
- •Pregnant or nursing
- •Significant concurrent kidney, liver, blood, or other disease
- •Recent heart attack or heart surgery
- •History of stroke, severe hypertension (high blood pressure), significant heart failure or cardiac arrhythmias
- •Significant lab abnormalities
- •Uncontrolled blood sugar
- •History of certain drug allergies
结局指标
主要结局
Mean trough SiDBP after 8 weeks of treatment
次要结局
- Safety
研究者
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