Evaluation the effectiveness of pomegranate and spearmint (Vomigramint) syrup on CINV

Phase 3

Recruiting

• Conditions: Condition 1: nausea and vomiting. Condition 2: Breast cancer.; Nausea and vomiting; Malignant neoplasm of breast of unspecified site, female

• Registration Number: IRCT20171118037516N1
• Lead Sponsor: Sari University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

More than 18 years-old aging
Documentary report for Breast cancer
At least one session of chemotherapy is done prior to intervention
Taking similar and one-day chemotherapy regimen
At least two sessions of chemotherapy is proceeding
History of any level of CINV (qualitative or quantative), despite taking routine anti-emetic drugs.

Exclusion Criteria

Total or upper abdomen radiotherapy, accompanying with chemotherapy simultaneously
Consumption therapeutic dosage of anti-coagulant agents
History of coagulopathic disorders
Taking anti- emetic drugs or methods, except those permitted drugs in this study
History of hypersensitivity to pomegranate or spearmint
Pomegranate or spearmint consumption during one week prior to intervention
Suffering from other cancers or metastatic breast cancer simultaneously
Having other problems or diseases causing nausea( e.g. Hypertension, Liver or Renal failure, Diabetes mellitous , Constipation )

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of nausea. Timepoint: Three days before intervention, One day after intervention, five days after intervention. Method of measurement: Visual analogue scale.