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Psychiatric assessment prior to and after switch from levetiracetam to brivaracetam: a questionnaire study

Conditions
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
Generalized idiopathic epilepsy and epileptic syndromes
G40.2
G40.3
Registration Number
DRKS00022128
Lead Sponsor
Epilepsiezentrum Kork
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
50
Inclusion Criteria

1. Participants with minimum age of 18 years and a diagnosis of epilepsy according to the 1989 International League Against Epilepsy (ILAE) classification
2. Participants receiving levetiracetam with an unchanged dose within 4 weeks.
3. The decision to switch from levetiracetam to brivaracetam will be made by the physician before and irrespective of his/her decision to include the participant in the study

Exclusion Criteria

1. Participants with known psychogenic non-epileptic seizures
2. Participants had already received brivaracetam in the past
3. Participants with a medical or a psychiatric condition that, in the opinion of the Investigator, could jeopardize or compromise the patient’s own ability to participate in the study: for example patients with status epilepticus, acute psychosis, acute respiratory distress, or participants with significant cognitive disorders etc.

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The aim of this study is to investigate a psychiatric change in epilepsy patients switching from levetiracetam to brivaracetam using the following parameters (Questionnaires): SCL-90-S, BDI II, AEP and Qolie31-P, between June 2020 and June 2021. Participants in the study will fill the questionnaires prior to and 8 days after switching to brivaracetam. <br><br>
Secondary Outcome Measures
NameTimeMethod
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