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临床试验/CTRI/2024/10/075451
CTRI/2024/10/075451尚未招募3 期

Effect of neuroplasty on different grades of median nerve dysfunction in carpal Tunnel syndrome

Department of Anaesthesiology and Critical CareJawaharlal Nehru Medical College AMUAligarh1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年11月15日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
To determine effect of neuroplasty on different grades of median nerve dysfunction in carpal tunnel syndrome using Numerical Rating Scale.

研究概览

简要总结

All enrolled patients who are not responding to pharmacotherapy after 6 weeks of treatment will undergo median nerve neuroplasty under USG guidance, in Pain Clinic, Department of Anaesthesiology and Critical Care, at the wrist using linear high frequency USG probe. The USG probe will be placed on the anterior aspect of wrist. The nerve will be seen as a single elliptical hyperechoic structure with internal hypochoic circles. USG grading will be done on the basis of cross sectional area of median nerve. Skin above the target will be infiltrated with 0.5ml of 2%Lidocaineto avoid pain due to needle insertion. Insert the needle, 22G and Som in length, using in plane approach from radial side of probe. 3ml solution containing 0.25% Bupivacaine +Triamcinolone(20mg) will be infiltrated around the nerve as real time injection in patients with CTS. Care will be taken to visualize the spread of drug which distend the perineum around the median nerve and to avoid needle penetration of nerve tissue and intravascular injury. All patients will be monitored in recovery room after intervention for 4 hours.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Willingness of patient to participate in study.
  • Patient age between 20-60 yrs 3)Clinically and Electrophysiologically diagnosed as Carpal Tunnel Syndrome since last 6 weeks.
  • Either sex.

排除标准

  • History of trauma.
  • Cervical radiculopathy.
  • Known patients of peripheral neuropathy of any other cause.
  • Pronator dysfunction 5)Patients having prior history of injectable corticosteroid 6) Patients with Motor dysfunction of the affected hand.

结局指标

主要结局

To determine effect of neuroplasty on different grades of median nerve dysfunction in carpal tunnel syndrome using Numerical Rating Scale.

时间窗: Patients will be assessed at 1;2;4 and 6 weeks post intervention

次要结局

  • To evaluate the effect of Neuroplasty on different grades of median nerve dysfunction using NCS.(2) To correlate the changes of median nerve cross sectional area on USG with Neurological Rating Scale and Nerve Conduction Studies before and after neuroplasty in different grades of median nerve dysfunction.)

研究者

发起方
Department of Anaesthesiology and Critical CareJawaharlal Nehru Medical College AMUAligarh
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Pooja Varshney

Department of Anaesthesiology,Jawaharlal Nehru Medical College,AMU,Aligarh UttarPradesh 202001 India

研究点 (1)

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