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临床试验/NCT04432051
NCT04432051已完成不适用

The Significance of Lung Ultrasonography in the Follow-up and Treatment of COVID-19 Patients With Respiratory Failure

Gaziosmanpasa Research and Education Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2020年5月26日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
100
试验地点
1
主要终点
Change in PO2 values

研究概览

简要总结

In COVID-19 patients hospitalized in the intensive care unit due to respiratory failure, lung ultrasonography will be tried to be given an appropriate position that will effectively use lung capacity and its effect on oxygenation will be investigated.

详细描述

In this study, the COVID-19 patients hospitalized in the intensive care unit due to respiratory failure will be evaluated. Participants will be divided into two groups as patients undergoing lung ultrasonography (Group Ultrasonography ) and those without lung ultrasonography (Group Control).

While performing lung ultrasonography, each hemithorax will be evaluated using anterior axillary line and posterior axillary line into anterior, lateral and posterior region, and each region will be divided into 6 quadrants, upper and lower. Each hemithorax will be scanned by the investigators, scored in 6 regions using a convex ultrasonography probe with the Lung Ultrasound Score (LUS score).

Participants in both groups will be evaluated by comparing arterial blood gas analyzes before examination (with/without ultrasonography), at the 2nd and 12th hours. Is there any change in arterial blood gas values such as PO2 and PCO2 at 0, 2 and 12 hours so that oxygenation and ventilation between Group Ultrasonograpy and Group Control will be evaluated?

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Triple (Participant, Care Provider, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients have been diagnosed with COVID 19
  • •Patients in the intensive care unit over the age of 18

排除标准

  • •Patients not diagnosed with COVID 19
  • •Patients with cardiac problems
  • •Patients with renal problems

研究组 & 干预措施

GRUP Control

Placebo Comparator

The daily respiratory system examination of COVID-19 patients who are hospitalized in the intensive care unit is performed and the necessary mechanical ventilation applications are performed by evaluating the arterial blood gas analysis.

干预措施: mechanical ventilator settings and position (Behavioral)

GRUP Ultrasonography

Active Comparator

The daily respiratory system examination of COVID-19 patients who are hospitalized in the intensive care unit is performed and the necessary mechanical ventilation applications are performed by evaluating the arterial blood gas analysis. However, the lung of the patient will be evaluated by ultrasound and the position to use the lung capacity most appropriately will be given.

干预措施: mechanical ventilator settings and position (Behavioral)

结局指标

主要结局

Change in PO2 values

时间窗: 12 hours

Effect of positioning on ultrasound guidance on oxygenation assessed by changes between pO2 values.

次要结局

  • Change in PCO2 values(12 hours)

研究者

申办方类型
Other Gov
责任方
Sponsor

研究点 (1)

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