The Use of Lung Ultrasonography in COVID-19 Patients

Not Applicable

Completed

• Conditions: Ultrasonography
• Interventions: Behavioral: mechanical ventilator settings and position

• Registration Number: NCT04432051
• Lead Sponsor: Gaziosmanpasa Research and Education Hospital

Brief Summary

In COVID-19 patients hospitalized in the intensive care unit due to respiratory failure, lung ultrasonography will be tried to be given an appropriate position that will effectively use lung capacity and its effect on oxygenation will be investigated.

Detailed Description

In this study, the COVID-19 patients hospitalized in the intensive care unit due to respiratory failure will be evaluated. Participants will be divided into two groups as patients undergoing lung ultrasonography (Group Ultrasonography ) and those without lung ultrasonography (Group Control).

While performing lung ultrasonography, each hemithorax will be evaluated using anterior axillary line and posterior axillary line into anterior, lateral and posterior region, and each region will be divided into 6 quadrants, upper and lower. Each hemithorax will be scanned by the investigators, scored in 6 regions using a convex ultrasonography probe with the Lung Ultrasound Score (LUS score).

Participants in both groups will be evaluated by comparing arterial blood gas analyzes before examination (with/without ultrasonography), at the 2nd and 12th hours. Is there any change in arterial blood gas values such as PO2 and PCO2 at 0, 2 and 12 hours so that oxygenation and ventilation between Group Ultrasonograpy and Group Control will be evaluated?

Study Timeline

• Study Start: 2020-05-26
• Study First Submitted: 2020-06-11
• Study First Submitted QC: 2020-06-12
• Study First Posted: 2020-06-16
• Status Verified: 2020-08
• Primary Completion: 2020-08-08
• Study Completion: 2020-08-10
• Last Update Submitted: 2022-12-21
• Last Update Posted: 2022-12-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients have been diagnosed with COVID 19
• Patients in the intensive care unit over the age of 18

Exclusion Criteria

• Patients not diagnosed with COVID 19
• Patients with cardiac problems
• Patients with renal problems

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
GRUP Control	mechanical ventilator settings and position	The daily respiratory system examination of COVID-19 patients who are hospitalized in the intensive care unit is performed and the necessary mechanical ventilation applications are performed by evaluating the arterial blood gas analysis.
GRUP Ultrasonography	mechanical ventilator settings and position	The daily respiratory system examination of COVID-19 patients who are hospitalized in the intensive care unit is performed and the necessary mechanical ventilation applications are performed by evaluating the arterial blood gas analysis. However, the lung of the patient will be evaluated by ultrasound and the position to use the lung capacity most appropriately will be given.

Primary Outcome Measures

Name	Time	Method
Change in PO2 values	12 hours	Effect of positioning on ultrasound guidance on oxygenation assessed by changes between pO2 values.

Secondary Outcome Measures

Name	Time	Method
Change in PCO2 values	12 hours	Effect of positioning on ultrasound guidance on ventilation assessed by changes between pCO2 values.

Trial Locations

Locations (1)

Gazoosmanpasa Education and Research Hospital; 🇹🇷 Istanbul, Turkey