跳至主要内容
临床试验/CTRI/2025/07/091518
CTRI/2025/07/091518尚未招募不适用

COMPARING THE ATTENUATION OF HEMODYNAMIC RESPONSE WITH I.V LABETALOL VS I.V LIGNOGAINE IN HYPERTENSIVE PATIENTS DURING LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION.

DR Januba S Subair1 个研究点 分布在 1 个国家目标入组 104 人开始时间: 2025年8月4日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
104
试验地点
1
主要终点
To evaluate the efficacy of 2different drugs in

研究概览

简要总结

The hemodynamic changes during intubation can accelerate the development of myocardial ischemia/arrhythmia/infarction and cerebral haemorrhage

The rise in blood pressure is due to increase in cardiac output rather than an increase in systemic vascular resistance, and is associated with the transient rise in central venous pressure.The aim of the study is to compare the efficacy of 2 different drugs for controlling these hemodynamic responses under Anesthestic techniques.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
24.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • All hypertensive patients between age of 24-80 ASA II.

排除标准

  • H/o chest pain/syncope/palpitations, any respiratory illness or he;antic or renal issues ASA III or more Pregnant and lactating women Morbid obesity Patient refusal.

结局指标

主要结局

To evaluate the efficacy of 2different drugs in

时间窗: 1, 3, 5, 7 minutes

attenuating the hemodynamic response to

时间窗: 1, 3, 5, 7 minutes

laryngoscopy and intubation

时间窗: 1, 3, 5, 7 minutes

次要结局

  • IV LABETALOL is better in attenuating hemodynamic responses when compared to IVLIGNOCAINE(1, 3, 5, 7 minutes)

研究者

发起方
DR Januba S Subair
申办方类型
Other [Self funding]
责任方
Principal Investigator
主要研究者

DR Januba S Subair

SRI RAMACHANDRA INSTITUTE OF HIGHER EDUCATION AND RESEARCH

研究点 (1)

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