Effect of oral ibuprofen for patent ductus arteriosus closure in infants
Not Applicable
- Conditions
- Closure of patent ductus arteriosus.patent dactus arterioussus
- Registration Number
- IRCT2013102215113N1
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
term infants (gestational age 37-42 weeks); Life Age = 3 days of patent ductus arteriosus by echocardiography ; Proof of completion of an informed consent form
Exclusion criteria: There is a reluctance to participate in the study ; Contraindications including ibuprofen creatinine> 8/1; platelet count less than 50,000 ;active gastrointestinal hemorrhage or intraventricular hemorrhage (confirmed by ultrasound); Antrkvlyt necrosis and sepsis; patent ductus arteriosus associated with other disorders; such as TORCH (intrauterine infection).
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gastrointestinal bleeding. Timepoint: Before treatment - after each drug administration. Method of measurement: Blood.;Platelet count. Timepoint: Before treatment - after each drug administration. Method of measurement: Blood.
- Secondary Outcome Measures
Name Time Method Serum creatinine. Timepoint: Before treatment - after each drug administration. Method of measurement: blood.