Community-based Accompaniment With Supervised Antiretrovirals in Lima, Peru
- Conditions
- HIVAIDSHIV Infections
- Registration Number
- NCT01070017
- Lead Sponsor
- Brigham and Women's Hospital
- Brief Summary
Using quantitative and qualitative data, this study will assess the impact of community accompaniment with supervised antiretrovirals (CASA) on HIV-positive individuals and community members in Lima, Peru.
- Detailed Description
Community-based accompaniment with directly observed antiretroviral therapy (DOT-HAART) may improve adherence and clinical outcomes among impoverished individuals starting HAART in resource-poor settings. Furthermore, the utilization of community health workers may build social capital. This is cluster-randomized trial, with randomization at the level of health centers. Individuals in both intervention and control clusters will receive community-based adherence support (monthly adherence visits) and standard care. In addition, individuals residing in intervention clusters will receive 12 months of community-based DOT-HAART. We will enroll patients as well as community members (health providers, treatment supporters, and community health workers) to assess individual and community-level outcomes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1244
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Proportion with suppressed HIV viral load after starting HAART among those receiving community-based DOT-HAART versus the control group. 18 and 24 months
- Secondary Outcome Measures
Name Time Method Identify mediating mechanisms of CASA effect on individual outcomes. 24 months Identify subgroups who respond best to CASA intervention. 24 months
Related Research Topics
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Trial Locations
- Locations (1)
Socios En Salud
🇵🇪Lima, Peru
Socios En Salud🇵🇪Lima, Peru