Perioperative Antibiotic Choices for Surgical Prophylaxis in Penicillin-allergic Pediatric Patients

Completed

• Conditions: Penicillin Allergy
• Interventions: Drug: Antibiotic

• Registration Number: NCT02036840
• Lead Sponsor: Joseph D. Tobias

Brief Summary

The proposed research project will retrospectively review the anesthetic records over the past 5 years and identify patients who present with a history of penicillin allergy or allergy to an antibiotic in the penicillin family. The reason for that history and the facts on which that allergy are noted will be determined. Additionally, the choice of antibiotic prophylaxis will be recorded and any adverse effect to that antibiotic noted. We will also note whether appropriate timing of the antibiotic is achieved.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01
• Study First Submitted: 2014-01-13
• Study First Submitted QC: 2014-01-13
• Study First Posted: 2014-01-15
• Primary Completion: 2014-11
• Study Completion: 2014-11
• Results First Submitted: 2015-02-12
• Status Verified: 2015-04
• Results First Submitted QC: 2015-04-20
• Last Update Submitted: 2015-04-20
• Results First Posted: 2015-04-22
• Last Update Posted: 2015-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 513

Inclusion Criteria

• Patients that are labeled as penicillin or penicillin family allergic.

Exclusion Criteria

• As neurosurgical patients routinely receive vancomycin at NCH for surgical prophylaxis, they will be excluded from the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Penicillin allergy	Antibiotic	-

Primary Outcome Measures

Name	Time	Method
Number of Subjects With Antibiotic Related Adverse Event	24 hours

Trial Locations

Locations (1)

Nationwide Children's Hospital; 🇺🇸 Columbus, Ohio, United States