NL-OMON34678招募中不适用
The significance of biomarkers in the blood in the diagnosis and the course of Alzheimer*s disease - Blood biomarkers for Alzheimer*s disease
niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 100 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patient inclusion criteria:
- •- Patients with Alzheimer's disease
- •- Mentally competent AD patient [Clinical Dementia Rating (CDR) scale 1]
- •- The diagnosis of probable Alzheimer's disease* should be made according to the NINCDS-
- •ADRDA criteria.
- •- Patients or carers should agree with the study (written informed consent is required form
- •patients or their carers).;Inclusion criteria control group (healthy subjects in group A):
- •- Men or women without cognitive or psychiatric disorders
- •- Mini-Mental State Examination (MMSE) score >= 28
排除标准
- •Patient exclusion criteria:
- •- Mentally incompetent AD patient [Clinical Dementia Rating (CDR) scale 2 and 3]
- •- Patients with infection or inflammatory disease less than 1 months ago.
- •- Patients with active malignancy.
- •- Patients with autoimmune disease (e.g. temporal arteritis, polymyalgia rheumatica).
- •- Patients who use immune modulating drugs (e.g. Immunocyanin, interferon gamma, immunoglobulin).
- •- Patients with renal dysfunction (MDRD <50)
- •- Patients with liver impairment
- •- Patients with decreased serum albumin <25 g / l;Exclusion criteria control group:
- •- Conform the patient exclusion criteria
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