Skip to main content
Clinical Trials/NCT02858596
NCT02858596
Completed
Not Applicable

The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on Clinical Outcomes, Specifically the Incidence of Aspiration Pneumonia and Postoperative Length of Stay

Hiroshima Kyoritsu Hospital0 sites136 target enrollmentJanuary 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Gastrostomy
Sponsor
Hiroshima Kyoritsu Hospital
Enrollment
136
Primary Endpoint
Incidence of aspiration pneumonia
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

Percutaneous endoscopic gastrostomy (PEG) is a minimally invasive procedure for long-term enteral tube feeding in patients with insufficient oral intake. Although peristomal site infection is often noted as the most common adverse event after PEG tube placements, it is seldom life-threatening and considered a minor adverse event. Feeding-related adverse events have been identified as the main cause of death after PEG, with up to 50% of postoperative early mortality (30 days) being attributed to aspiration pneumonia. This may be related to the persistence of gastroesophageal reflux (GER) of enteral feed after gastrostomy, even though PEG have been demonstrated to be superior to nasogastric tube feeding in terms of preventing GER. It has been more than a decade since semi-solid feeds were developed as an alternative to conventional liquid feeds to prevent feeding-related adverse events. Unfortunately, there is limited published literature on this topic despite the wide usage of this feeding method in Japan. Amidst the growing popularity of this method and the introduction of National Healthcare Insurance coverage for semi-solid feed prescriptions, we initiated a semi-solid feed protocol along with our existing post-PEG feeding protocols in 2014.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
December 2015
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Wong Toh Yoon

Chief Gastroenterologist

Hiroshima Kyoritsu Hospital

Eligibility Criteria

Inclusion Criteria

  • Patients receiving gastrostomy tube placement in our hospital for enteral nutrition.

Exclusion Criteria

  • Patients receiving gastrostomy tube placement for decompression
  • Patients with no gut usage more than 2 weeks before procedure

Outcomes

Primary Outcomes

Incidence of aspiration pneumonia

Time Frame: through study completion, average 90 days postoperation

Secondary Outcomes

  • Postoperative length of stay(through study completion, average 90 days postoperation)

Similar Trials