The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on Clinical Outcomes, Specifically the Incidence of Aspiration Pneumonia and Postoperative Length of Stay
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Gastrostomy
- Sponsor
- Hiroshima Kyoritsu Hospital
- Enrollment
- 136
- Primary Endpoint
- Incidence of aspiration pneumonia
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Percutaneous endoscopic gastrostomy (PEG) is a minimally invasive procedure for long-term enteral tube feeding in patients with insufficient oral intake. Although peristomal site infection is often noted as the most common adverse event after PEG tube placements, it is seldom life-threatening and considered a minor adverse event. Feeding-related adverse events have been identified as the main cause of death after PEG, with up to 50% of postoperative early mortality (30 days) being attributed to aspiration pneumonia. This may be related to the persistence of gastroesophageal reflux (GER) of enteral feed after gastrostomy, even though PEG have been demonstrated to be superior to nasogastric tube feeding in terms of preventing GER. It has been more than a decade since semi-solid feeds were developed as an alternative to conventional liquid feeds to prevent feeding-related adverse events. Unfortunately, there is limited published literature on this topic despite the wide usage of this feeding method in Japan. Amidst the growing popularity of this method and the introduction of National Healthcare Insurance coverage for semi-solid feed prescriptions, we initiated a semi-solid feed protocol along with our existing post-PEG feeding protocols in 2014.
Investigators
Wong Toh Yoon
Chief Gastroenterologist
Hiroshima Kyoritsu Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients receiving gastrostomy tube placement in our hospital for enteral nutrition.
Exclusion Criteria
- •Patients receiving gastrostomy tube placement for decompression
- •Patients with no gut usage more than 2 weeks before procedure
Outcomes
Primary Outcomes
Incidence of aspiration pneumonia
Time Frame: through study completion, average 90 days postoperation
Secondary Outcomes
- Postoperative length of stay(through study completion, average 90 days postoperation)