Pioglitazone for bipolar mixed or depressive episode
Phase 2
- Conditions
- Bipolar disorder.F31.3-6
- Registration Number
- IRCT201211211556N46
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
The patients who were diagnosed with depressive (Hamilton rating scale >=20) or mixed (both Hamilton >=20 and Mania>=18) based on DSM-IV-TR criteria will be included in the study after obtaining informed consent.
Exclusion criteria
1. Disorders in other axes
2. Other psychotropic drugs
3. Taking antidepressants in the past month
4. Thyroid disorder
5. ECT in the previous two months
6. History of cardiovascular disorders
7. Pregnant or lactating women
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in depression. Timepoint: Week 6. Method of measurement: Hamilton Depression Rating Scale.
- Secondary Outcome Measures
Name Time Method Reduction in depression. Timepoint: Week 2 and 4. Method of measurement: Hamilton Depression Rating Scale.;Reduction in mania. Timepoint: Weeks 2, 4 and 6. Method of measurement: Young Mania Rating Scale.