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Clinical Trials/NCT03551158
NCT03551158
Completed
Not Applicable

The Search for Non-invasive Determinants of Response to Ablation of Atrial Fibrillation. Non-invasive Evaluation of Left Atrium Anatomy and Function With Three Dimensional Echocardiography: Comparison With Cardiac CT and MRI

Universitair Ziekenhuis Brussel1 site in 1 country300 target enrollmentNovember 28, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Atrial Fibrillation
Sponsor
Universitair Ziekenhuis Brussel
Enrollment
300
Locations
1
Primary Endpoint
Atrial fibrillation recurrence
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

The aim of the study is to evaluate the accuracy and reproducibility of the left atrium (LA) anatomy and function in different populations and in patients with atrial fibrillation who have undergone cryoballoon ablation.

Detailed Description

This study implies three parts. The first part of the study aims to evaluate the variability and reproducibility of rest two - and three-dimensional echocardiography for the left atrium anatomy and function and to assess their correlation with clinical variables. The second part of the study aims to evaluate the accuracy and reproducibility of the left atrium anatomy and function using echocardiography and to validate it with cardiac CT. Moreover, the study aims to evaluate which parameters can predict the recurrence of atrial fibrillation in patients who have undergone atrial fibrillation ablation. The third part of the study aims to assess the accuracy and variability of echocardiographic measurements compared to cardiac magnetic resonance and to find predictors of recurrence after cryoballoon ablation for atrial fibrillation.

Registry
clinicaltrials.gov
Start Date
November 28, 2017
End Date
December 28, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • subsequent group of patients sent to the echocardiography laboratory for any indication/patients who have undergone a cryoballoon ablation
  • older than 18 years old

Exclusion Criteria

  • inadequate image quality during echocardiography, contraindications for computed tomography or cardiac magnetic resonance

Outcomes

Primary Outcomes

Atrial fibrillation recurrence

Time Frame: 1 year

Predictors of atrial fibrillation recurrence after ablation

Study Sites (1)

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