Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery

Completed

• Conditions: Enhanced Recovery After Surgery; Early Mobilization; Anesthesia; Surgery-Complications; Colorectal
• Interventions: Procedure: Early mobilization; Procedure: No early mobilization

• Registration Number: NCT06065696
• Lead Sponsor: Indonesia University

Brief Summary

Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in Enhanced Recovery After Surgery protocol for colorectal surgery in our hospital: post operative nausea and vomiting (PONV) prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management. Although early mobilization affected by postoperative pain, vomiting and nausea, and fluid balance management, nonetheless, there is no clear evidence of how much each of these components will affect early mobilization.

Detailed Description

Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in ERAS protocol for colorectal surgery in our hospital: PONV prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management. Although early mobilization affected by postoperative pain, vomiting and nausea, and fluid balance management, nonetheless, there is no clear evidence of how much each of these components will affect early mobilization. This study was a retrospective cohort study by collecting secondary data from patients underwent elective colorectal surgery in our hospital from January 2020 to December 2022. The outcomes assessed were early mobilization rate and factors affecting it (PONV prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management).

Study Timeline

• Study Start: 2023-02-01
• Primary Completion: 2023-04-30
• Study Completion: 2023-04-30
• Study First Submitted: 2023-07-31
• Status Verified: 2023-09
• Study First Submitted QC: 2023-09-30
• Last Update Submitted: 2023-09-30
• Study First Posted: 2023-10-04
• Last Update Posted: 2023-10-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 343

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Early mobilization	Early mobilization	Patients who achieved early mobilization after colorectal surgery
No early mobilization	No early mobilization	Patients who did not achieve early mobilization after colorectal surgery

Primary Outcome Measures

Name	Time	Method
Early mobilization	Within 24 hours after surgery	Number of patients who can walk within 24 hours after surgery
Intraoperative fluid management	Given during intraoperative period	Number of patients who achieved fluid balance of zero or near zero
PONV prophylaxis	Given during intraoperative period	Number of patients who received prophylaxis given for PONV
Postoperative pain management	Immediately after surgery until discharge, assessed until hospital discharge, up to 50 days	Number of patients who received postoperative pain management without opioid
Multimodal analgesia	Given during intraoperative period	Number of patients who got multimodal analgesia, which consists of epidural anesthesia or peripheral nerve block

Trial Locations

Locations (1)

Cipto Mangunkusumo Central National Hospital; 🇮🇩 Jakarta Pusat, DKI Jakarta, Indonesia