FINESSE Trial – Filtration In the Neuropathy of End Stage kidney disease Symptom Evolutio

Not Applicable

Recruiting

• Conditions: raemic neuropathy; End Stage Kidney Disease; Uraemic neuropathy; Renal and Urogenital - Kidney disease; Other - Conditions of unknown or disputed aetiology (such as chronic fatigue syndrome/myalgic encephalomyelitis)

• Registration Number: ACTRN12609000615280
• Lead Sponsor: Statewide Renal Services

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-07-22
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Incident or prevalent patients requiring maintenance haemodialysis therapy for end stage kidney disease.
2. Aged 18 years or older
3. Suitable for either haemodiafiltration or standard dialysis in the view of the treating physician
4. Agreeable to randomisation

Exclusion Criteria

Patients will be excluded if, in the opinion or knowledge of the responsible clinician:
1. Life expectancy is less than 6 months.
2. Definite plans to undergo renal transplantation, transfer to a non-study site, transfer to peritoneal dialysis or transfer to home haemodialysis within 12 months of entry to the study.
3. Unable or unwilling to complete neuropathy staging, including nerve conduction studies.
4. Receiving haemodiafiltration

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean annual change in neuropathy as measured by the Total Neuropathy Score[12, 24, 36 and 48 months after randomisation]