Evaluation of Vena Cava Ultrasound for Predicting Venous Congestion in Critically Ill Patients: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- SELF
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- The primary outcome of interest is venous congestion defined as presence of mild congestion in atleast one of the hepatic portal and renal doppler assessments
研究概览
简要总结
This prospective observational study aims to evaluate the utility of vena cava ultrasound in predicting systemic venous congestion in critically ill invasively ventilated patients admitted to a mixed medical-surgical ICU Traditional markers like central venous pressure have limitations and while the VEXUS (Venous Excess Ultrasound) grading system has shown promise in cardiac surgical patients its applicability in non-cardiac ICU patients remains unclear
The primary objective is to assess the predictive ability of the maximum anteroposterior diameter of the inferior vena cava (IVCAP) for venous congestion, defined by at least mild abnormalities in hepatic portal or renal venous Doppler
Secondary objectives include comparing diagnostic accuracy between IVCAP lateral diameter IVCLat their ratio IVCAP Lat and IVC distensibility index along with evaluating their correlation with acute kidney injury AKI
Adult patients m ore than18 years expected to remain ventilated for more than 48 hours will undergo serial ultrasound evaluations over 5 days Venous Doppler studies and IVC measurements will be performed with standardized protocols using B-mode and Doppler imaging AKI will be assessed as per KDIGO criteria and correlated with ultrasound findings using logistic regression and ROC analysis
The study will enroll 64 patients as determined by sample size calculations based on expected AUC values Results aim to establish optimal IVC diameter cutoffs and validate vena cava ultrasound as a non-invasive diagnostic tool for venous congestion and its association with AKI in the ICU setting
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients aged 18 years or older who are admitted to the ICU invasively ventilated and expected to stay for at least 48 hours will be eligible for inclusion.
排除标准
- •Patients will be excluded if they are pregnant have known anatomical anomalies or obstruction of the IVC present with unreliable IVC windows on ultrasound liver cirrhosis or if consent is refused.
结局指标
主要结局
The primary outcome of interest is venous congestion defined as presence of mild congestion in atleast one of the hepatic portal and renal doppler assessments
时间窗: 5days
次要结局
- The primary outcome of interest is venous congestion defined as presence of mild congestion in atleast one of the hepatic, portal and renal doppler assessments.(5days)