Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Glucose Tolerance or Mild Type 2 Diabetes

Not Applicable

• Conditions: Impaired Glucose Tolerance; Diabetes Mellitus

• Registration Number: NCT00417950
• Lead Sponsor: Taichung Veterans General Hospital

Brief Summary

To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes.

Detailed Description

Not available

Study Timeline

• Status Verified: 2007-01
• Study Start: 2007-01
• Study First Submitted: 2007-01-01
• Study First Submitted QC: 2007-01-03
• Last Update Submitted: 2007-01-03
• Study First Posted: 2007-01-04
• Last Update Posted: 2007-01-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Subjects with mild diabetes without prior medications or impaired glucose tolerance

Exclusion Criteria

• Pregnancy
• Recent major cardiac, renal and hepatic disease
• Intolerance to alcohol
• Allergy to acarbose treatment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Postprandial hyperglycemia

Secondary Outcome Measures

Name	Time	Method
Postprandial inflammatory responses
Postprandial oxidative stress

Trial Locations

Locations (1)

Taichung Veterans General Hospital; 🇨🇳 Taichung, Taiwan