NCT04664556招募中不适用
Population-based Nationwide Study on Invasive Pneumococcal Infections Among Children (0-18 Years) in France
Association Clinique Thérapeutique Infantile du val de Marne2 个研究点 分布在 1 个国家目标入组 2,500 人开始时间: 2010年12月13日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,500
- 试验地点
- 2
- 主要终点
- Severity of invasive pneumococcal disease
研究概览
简要总结
After 7 then 13 valent pneumococcal conjugate vaccine (PCV) implementation in France in children, we will evaluate the impact of this vaccination on invasive pneumococcal disease (IPD). We will describe the clinical characteristics of IPD, pneumococcus serotyping, underlying conditions and vaccination status.
详细描述
For children under 18, hospitalized for IPD, the following data will be analyzed: risk factors, vaccination status, severity signs , treatment during hospitalization, biological analysis, the clinical location of the disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Day 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Isolate of Streptococcus pneumoniae from at least one blood culture, or pleural fluid, or joint fluid, or cerebrospinal fluid or other normally sterile body site, or if there is a positive blood polymerase chain reaction (PCR).
排除标准
- •Pneumococcal strain not transmetted to National Reference Center for Pneumococci or to Regional Pneumococci Observatory
结局指标
主要结局
Severity of invasive pneumococcal disease
时间窗: before hospital discharge
Number of severe cases according to age and pneumococcal serotypes distribution
次要结局
- Impact of vaccines(before hospital discharge)
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
1 期
Impact of the 7 Valent Pneumococcal Conjugate Vaccine (7vPCV) on Nasopharyngeal Carriage of Streptococcus Pneumoniae in Healthy Jordanian InfantsStreptococcus PneumoniaeNCT00900978German-Jordanian University377
进行中（未招募）
4 期
Evaluating the Effectiveness of a Pneumococcal Immunisation Campaign in a Camp for Internally Displaced PeoplePneumococcal InfectionsNCT04945681London School of Hygiene and Tropical Medicine2,882
已完成
不适用
A Study to Assess the Carriage of Pneumococci in Children Aged ≤8 Years, and Their Household ContactsInfection ImmunizationNCT03407690Public Health England280
已完成
2 期
PNEUMOCELL - Conjugated Pneumococcal Vaccination in Patients With Immunoglobulin G-deficiencyIgG DeficiencyNCT01847781Karolinska University Hospital20
招募中
4 期
Clinical Trial Assessing the Immunogenicity of an Anti-pneumococcal Vaccination Strategy (PCV13+PPV23 Versus PREVENAR20) in Adult Patients Treated for a LymphomaVaccineStreptococcus PneumoniaeLymphoma, Non-HodgkinNCT04460235Poitiers University Hospital160