MedPath

Safety and Efficacy of the Bi-Aspheric Monofocal IOL

Recruiting
Conditions
Cataract
Interventions
Device: aspicio Monofocal IOL
Registration Number
NCT06380478
Lead Sponsor
ICARES Medicus, Inc.
Brief Summary

This is an observational, single-center, non-control, open-label post-marketing study. Patients implanted with an aspicio™ Monofocal Intraocular Lens will be scheduled for a follow-up visit at least 3 months after the surgery to undergo a routine basic ophthalmological examination.

Detailed Description

This is an observational, single-center, non-control, open-label post-marketing study. Patients implanted with an aspicio™ Monofocal Intraocular Lens will be scheduled for a single visit in the facilities of Chang Gung University Hospital at least 3 months after the surgery. Patients will undergo a routine basic ophthalmological examination.

Additionally, and retrospectively, the patients' medical records will be reviewed to obtain information on visual acuity and adverse events at postoperative visit carried out 1 month after surgery.

The data corresponding to the preoperative values of corneal curvature (flat meridian, curved meridian and axes), axial length measured by biometry, visual acuity and those corresponding to the implanted IOL will also be collected from the medical records.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
30
Inclusion Criteria
  1. Subjects 18 years of age or older who have been implanted with aspicio™ monofocal intraocular lens in at least 1 eye
  2. Willingness to cooperate with and complete all post-operative visits
  3. Ability to comprehend and sign an informed consent
Exclusion Criteria
  1. Any pathology that could reduce Visual Acuity (VA) (including amblyopia, severe corneal dystrophy, diabetic retinopathy, extremely narrow anterior chamber depth, microphthalmos, clinically significant macular/RPE changes, retinal detachment, corneal transplant, chronic sever uveitis, choroidal hemorrhage, recurrent severe inflammation of the anterior or posterior segment of unknown etiology, iris neovascularization, medically controlled or uncontrolled glaucoma, clinically significant macular degeneration, or diagnosis of pseudoexfoliation).
  2. Previous ocular surgery (including YAG-laser) or trauma
  3. Clinically significant irregular astigmatism
  4. Concomitant severe eye disease
  5. Pregnant or lactating
  6. Any other ocular or systemic condition which, in the opinion of the investigator, should exclude the subject from the study
  7. Concurrent participation in another drug or device investigation
  8. May be expected to require other ocular surgery during the study

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
aspicio Monofocal IOLaspicio Monofocal IOLA bi-aspheric monofocal IOL is implanted through preloaded IOL Delivery System in the capsular bag in the posterior chamber of the eye during cataract surgery
Primary Outcome Measures
NameTimeMethod
Defocus curve3 months after implantation

Photopic monocular defocus curve, -4.0 D \~ +2.0 D

CDVA3 months after implantation

Photopic monocular best corrected distance visual acuity (CDVA), 400cm

Secondary Outcome Measures
NameTimeMethod
AE3 months after implantation

Signs of inflammation and AEs

CIVA3 months after implantation

Photopic monocular corrected intermediate visual acuity (CIVA), 60cm

Satisfaction questionnaire3 months after implantation

Satisfaction questionnaire

UDVA3 months after implantation

Photopic monocular uncorrected distance visual acuity (UDVA), 400cm

UIVA3 months after implantation

Photopic monocular uncorrected intermediate visual acuity (UIVA), 60cm

IOL glistening3 months after implantation

IOL glistening observation

PCO3 months after implantation

Posterior Capsular Opacification observation

Trial Locations

Locations (1)

Chang Gung University Hospital

🇨🇳

Taoyuan, Guishan District, Taiwan

© Copyright 2025. All Rights Reserved by MedPath