Brain Volumes of Very Low Birth Weight Infants Measured by Cranial Ultrasonography
- Conditions
- Infant, Premature
- Registration Number
- NCT02848755
- Lead Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
- Brief Summary
Neonatal cranial ultrasound (US) remains the method of choice to detect brain injury in high risk preterm infants on neonatal intensive care units (NICU). It is a non-invasive, inexpensive bedside tool and examinations can be repeated as often as necessary without major disturbance of vulnerable infants. The anterior and posterior fontanelles from excellent acoustic windows to examine the deep midline and periventricular regions of the brain.Some data demonstrated that cerebral palsy can be accurately predicted with US. However, cranial US is not very suitable for investigating cortical regions or structures in the posterior fossa. There is limited data for very preterm infants.The investigators aimed to measure ventricular index, cranial height, biparietal diameter and calculate brain volume in a huge number of infants.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 341
- both gender
- <1500 gr <32 week-
- 1-28 days neonates
- Anomalies and no viability
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method measurements of ventricular indexes of preterm infants 12 months measuring distance with 2D USG
measurements of brain volumes of preterm infants 12 months subtracting the ventricular volumes from the total brain volume measured with 2D
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Zekai Tahir Burak NICU
🇹🇷Ankara, Turkey