NCT02731391Unknown不适用
Clinical Research on Bowel Symptoms of Patients With Pelvic Organ Prolapse
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- change in the prevalence of bowel symptoms
研究概览
简要总结
To study the prevalence of bowel symptoms in patients with pelvic organ prolapse.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •The patients with stage>2 POP are recruited.The patients are all received surgeries, which include transvaginal synthetic mesh surgery, the sacral fixation, tissue repair surgery and colpocleisis.
排除标准
- •Gestation；
- •Inflammatory bowel disease；
- •Slow transit constipation diagnosed by Colonic transit test；
- •Unable to follow up.
研究组 & 干预措施
Mesh repairment
Experimental
patients undergoing pelvic floor Reconstruction using mesh
干预措施: Pelvic floor reconstruction（with or without mesh） (Procedure)
Tradition Neoplasty
Active Comparator
patients undergoing traditional surgical approaches
干预措施: Pelvic floor reconstruction（with or without mesh） (Procedure)
结局指标
主要结局
change in the prevalence of bowel symptoms
时间窗: baseline,1,3,6,12 months after operation.
change in the severity of intestinal symptoms
时间窗: baseline,1,3,6,12 months after operation.
assessed by Birmingham Bowel and Urinary Symptoms Questionnaire
次要结局
- change in the quality of life(baseline,1,3,6,12 months after operation.)
- length of the high-pressure zone recorded by anorectal manometry(baseline and 12 months after operation)
- rectoanal inhibitory reflex recorded by anorectal manometry(baseline and 12 months after operation)
- Rectal-Vaginal pressure interval during maximum Vasalva(baseline and 6 months after operation)
研究者
Tan Cheng
doctor
Peking University People's Hospital
研究点 (1)
Loading locations...
相似试验
终止
不适用
Observing Pelvic Organ Prolapse Symptoms And Treatment OutcomesGenital ProlapseNCT00784602Melissa Fischer, MD301
已完成
不适用
Evolution of Symptoms After Anterior Sacrospinofixation by Autologous TissuesPelvic Organ ProlapseNCT04270188Hospices Civils de Lyon66
已完成
不适用
Evolution of Symptoms After Sacrospinofixation With Posterior Isthmic BandApical ProlapseNCT03911778Hospices Civils de Lyon33
Unknown
不适用
Laparoscopic Sacral Colpopexy Versus Modified Total Pelvic Floor Reconstructive Surgery for Apical Prolapse Stage III-IVUterine ProlapseVault ProlapseNCT01762384Peking Union Medical College Hospital100
已完成
2 期
Clinical and Urodynamic Evaluation of Surgical Repair of Pelvic Organ Prolapse Associated With Lower Urinary Tract SymptomsPelvic Organ ProlapseNCT04793126Ain Shams University83