A Long-term, Prospective, Observational Cohort of Patients With Chronic Pulmonary Disease
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Rate of acute exacerbations
研究概览
简要总结
This is a longitudinal study of following chronic pulmonary disease patients to observe and predict the clinical outcomes of these patients.
详细描述
In patients with chronic pulmonary disease, impaired pulmonary function and limited exercise capacity, is a complex clinical syndrome with a wide range of underlying causes, which may result in worse quality of life and high economic burden. This is a longitudinal study of following chronic pulmonary disease patients, recording the clinical, pathophysiology, and psychological parameters, to observe and predict the clinical outcomes of these patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-80, males and females
- •Patients are diagnosed as the obstructive pulmonary disease according to the clinical practice.
- •Willing to participate in the study.
- •Being able to provide informed consent.
排除标准
- •Subjects with severe heart failure, severe arrhythmias, unstable angina, and malignant comorbidities.
- •Subjects with significantly impaired cognitive function and are unable to fulfill the study requirement (unable to provide informed consent)
- •Subjects who participated in another trial within 30 days prior to the planned start of the study
- •Subjects with cancer or have had cancer in the 5 years prior to study entry.
结局指标
主要结局
Rate of acute exacerbations
时间窗: 1 year
The rate of exacerbations within 1 year of these patients will be tracked.
次要结局
- Survival(1 year)
- Health related quality of life: questionnaires(1 year)
- 6-minute walk test(1 year)
- Forced expiratory volume in 1 second(1 year)
研究者
Guan Lili
Principal Investigator
The First Affiliated Hospital of Guangzhou Medical University