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Post Approval Study of the Commercially Available U-Motion II+ Acetabular System and UTF Reduced Stem

Active, not recruiting
Conditions
Osteoarthritis
Interventions
Device: U-Motion II+ Acetabular System
Registration Number
NCT02761499
Lead Sponsor
United Orthopedic Corporation
Brief Summary

This is a prospective, single arm, multi-center, post-approval study designed to evaluate the short and long term clinical performance and safety in subjects receiving primary total hip arthroplasty (THA) with the U-Motion II+ Acetabular System and UTF Reduced Stem.

Detailed Description

This is a prospective, single arm, multi-center, post-approval study designed to evaluate the short and long term clinical performance and safety in subjects receiving primary total hip arthroplasty (THA) with the U-Motion II+ Acetabular System and UTF Reduced Stem. The acetabular and femoral components will be uncemented. Study outcomes will be analyzed and published when 1.) all enrolled and implanted subjects complete their 6-week follow up, 2.) all implanted subjects complete their 2-year follow up, 3.) at the conclusion of the study.

It is anticipated that up to 200 subjects will be enrolled at up to 5 sites. The subjects will be evaluated at predetermined intervals: baseline, procedure/ discharge and 6 weeks, 3 months, 6 months, 12 months, and 24 months post treatment for primary analysis and annually up to 5 years for device survivorship. The estimated study duration from first enrollment through completion of the final report is expected to be approximately 7 years.

This study will be conducted at up to 5 investigational sites in the United States with previous clinical research experience and with adequate population of orthopedic patients requiring primary total hip arthroplasty.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
200
Inclusion Criteria

Subjects must meet all of the following criteria to be considered for inclusion in the study.

  1. Subject is between 18 and 75 years of age
  2. Subject is indicated for a unilateral or bilateral total hip arthroplasty (THA) based on the approved labeling of the device
  3. Subject has no history of previous prosthetic replacement device or orthopedic surgeries on the operative hip
  4. Subject is willing and able to provide informed consent to participate in the study;
  5. Subject is willing and able to understand the purpose of the study, his/her role, and is available to return to the clinic/hospital for all required follow-up visits;
Exclusion Criteria
  • Subjects will be excluded if, in the opinion of the Investigator, the subject does not qualify based on approved labeling requirements or Subject Inclusion criteria.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Total Hip ArthroplastyU-Motion II+ Acetabular SystemThe United Hip System consist of several components, and for this clinical evaluation it includes the U-Motion II+ Acetabular System (1) U-Motion II+ acetabular cup, (2) U-Motion II+ acetabular liner, (3) Cobalt-Chrome or BIOLOX delta ceramic femoral heads, and the 4) UTF Reduced Stem.
Primary Outcome Measures
NameTimeMethod
Operative Success2 Years

Post-operative increase in Harris Hip Score of \> 20 points + radiographically stable implant + no additional femoral reconstruction stable implant + no additional femoral reconstruction

Secondary Outcome Measures
NameTimeMethod
Operative TimeProcedure

Operative time in minutes

Subject SatisfactionProcedure, 6 weeks, 3 months, 6 months, 12 months, 2 Years, 3 Years, 4 Years and 5 Years.

To assess the subject's satisfaction with their hip implant

VAS Hip PainBaseline, Procedure, 6 weeks, 3 months, 6 months, 12 months, 2 Years, 3 Years, 4 Years and 5 Years.

Improvement in Hip Pain VAS scores out to 5 years

Device Related Adverse EventsProcedure, 6 weeks, 3 months, 6 months, 12 months, 2 Years, 3 Years, 4 Years and 5 Years.

Device related adverse events will be assessed at each follow up visit.

Length of hospital stay2 Years

Length of stay in hours or days

Estimated Blood Loss (EBL)2 Years

Estimated blood loss in cc's

HOOS QuestionnaireBaseline, Procedure, 6 weeks, 3 months, 6 months, 12 months, 2 Years, 3 Years, 4 Years and 5 Years.

To assess patient-relevant outcomes in five separate subscales (pain, symptoms, activity of daily living, sport and recreation function and hip related quality of life).

Harris Hip ScoreBaseline, Procedure, 6 weeks, 3 months, 6 months, 12 months, 2 Years, 3 Years, 4 Years and 5 Years.

Assess outcome of total hip replacement

Trial Locations

Locations (6)

Kenosha Orthopedics

🇺🇸

Kenosha, Wisconsin, United States

Jacksonville Orthopaedic Institute

🇺🇸

Jacksonville, Florida, United States

Joint Replacement Institute

🇺🇸

Naples, Florida, United States

Penn Orthopaedics

🇺🇸

Philadelphia, Pennsylvania, United States

Ortho Dayton

🇺🇸

Dayton, Ohio, United States

Hospital for Special Surgery

🇺🇸

New York, New York, United States

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