Therapeutic effect of percutaneous electroacupuncture combined with adaptive biofeedback in the treatment of outlet obstructive constipatio

Not Applicable

• Conditions: outlet obstructed constipation

• Registration Number: ITMCTR2000003814
• Lead Sponsor: Anhui Provincial Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. There was evidence of outlet obstruction and met Rome IV diagnostic criteria for functional constipation
2. Aged 18 to 65 years old male and female;
3. Colonoscopy was performed in a Grade-A hospital one year before the enrollment to exclude intestinal cancer, ulcer, inflammation or other organic intestinal diseases;
4. B-ultrasound examination was performed in a Grade-A hospital one year before admission to exclude hepatobiliary and pancreatic diseases;
5. The patients with normal ECG examination in our center one month before admission (QT interval was within normal range).

Exclusion Criteria

1. Have a history of abdominal surgery;
2. Organic diseases of digestive system (including polyps, inflammatory bowel disease, tumor, celiac disease, lactose intolerance, etc.);
3. Any antispasmodic and analgesic drugs, gastrointestinal motility drugs, acid inhibitors, microecological agents, antibiotics, antidepressants, etc. were used within 2 weeks before enrollment;
4. B ultrasound examination of liver, gallbladder and pancreas diseases;
5. People with hypertension and unstable blood pressure control;
6. Patients with diabetes mellitus, thyroid disease, systemic sclerosis, systemic lupus erythematosus, etc;
7. Patients with severe psychological disorders;
8. pregnant women, lactating women or planned pregnancies;
9. There are allergic patients taking polyethylene glycol 4000 powder;
10. Observation contents:
(1) Basic information collection;
(2) Constipation symptom severity score pac-sym;
(3) Constipation quality of life score pac-qol;
(4) Anal sphincter pressure during defecation;
(5) Changes of serum psychosomatic neurotransmitters (conditional units).

Study & Design

• Study Type: Interventional study
• Study Design: Not specified