Feasibility of adding Hydrogen gas inhalation to relieve the acute toxicities from concurrent chemoradiotherapy (CCRT) in locally advanced head and neck cancer (LAHNC)
Phase 2
- Conditions
- Concurrent chemoradiotherapy (CCRT) in locally advanced head and neck cancer (LAHNC) induced acute toxicities.Hydrogen gas, Hydrogen gas Inhalation, Concurrent chemoradiotherapy, CCRT, Locally advanced head and neck cancer, Acute toxicities
- Registration Number
- TCTR20230627002
- Lead Sponsor
- Faculty of Medicine, Chiang Mai University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
1. Loco-regional advanced stage HNC
2. Histologically-proven diagnosis of HNC
3. Eastern Cooperative Oncology Group (ECOG) performance status 0-2
4. Able to provide informed consent
Exclusion Criteria
1. Distant metastasis or locoregional recurrence disease
2. Contraindications to RT or chemotherapy or Hydrogen gas inhalation
3. Previous head and neck irradiation
4. Previous head and neck surgery (except biopsy)
5. Patients with tracheostomy tube
6. Patients with respiratory disease e.g. asthma, COPD, Pneumonia, Lung cancer
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method