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Clinical Trials/NCT01084824
NCT01084824
Completed
Not Applicable

A Randomized Clinical Trial Examining the Efficacy of Treatment of Cutaneous Verruca Vulgaris in Adult Patients With Combined Liquid Nitrogen Cryotherapy and Topically Applied Cantharidin

North Idaho Dermatology1 site in 1 country70 target enrollmentJune 2007
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ConditionsVerruca Vulgaris
InterventionsLiquid nitrogen and cantharidinLiquid nitrogen and topical placebo
DrugsLiquid nitrogen and cantharidinLiquid nitrogen and topical placebo

Overview

Phase
Not Applicable
Intervention
Liquid nitrogen and cantharidin
Conditions
Verruca Vulgaris
Sponsor
North Idaho Dermatology
Enrollment
70
Locations
1
Primary Endpoint
Percentage of common warts cleared
Status
Completed
Last Updated
16 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of the study was to see if liquid nitrogen, a commonly used treatment for warts, is more effective if it is used alone, or if it is more effective if combined with cantharidin, a topical treatment also commonly used for warts (verruca vulgaris).

Registry
clinicaltrials.gov
Start Date
June 2007
End Date
September 2008
Last Updated
16 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
North Idaho Dermatology

Eligibility Criteria

Inclusion Criteria

  • •common warts on non-genital, non-facial skin
  • •otherwise healthy
  • •between 18-65 and able to give informed consent
  • •capable of tolerating treatment

Exclusion Criteria

  • •Poor tolerance or sensitivity to treatments in study
  • •\<18 years old; \>65 years old
  • •verruca plana or condyloma acuminata
  • •immunosuppression or immune dysfunction
  • •significant peripheral vascular disease
  • •significant sensitivity to cold
  • •epidermodysplasia verruciformis
  • •mosaiform warts or periungual warts

Arms & Interventions

Liquid nitrogen and canthardin

Liquid nitrogen applied to wart(s), then cantharidin 1% topical applied afterwards.

Intervention: Liquid nitrogen and cantharidin

Liquid nitrogen and placebo

Liquid nitrogen applied to wart(s) then placebo vehicle afterwards.

Intervention: Liquid nitrogen and topical placebo

Outcomes

Primary Outcomes

Percentage of common warts cleared

Time Frame: 12 weeks

Percentage of treated warts cleared with treatment, as measured with dermatoscopic examination, after 12 weeks.

Study Sites (1)

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